August 9, 2024

Automated Panel Mixing with the Parhelia Spatial Station™ for Spatial Biology and Flow Cytometry. Copy 4

Applications

Spatial Biology

Spatial biology is a promising field with cancer, neuroscience, immunology, and developmental biology applications. Spatial insights complement other 'omics approaches, offering unique perspectives on biological system organization. Challenges include complexity, lack of standardized methods, data integration, expertise, sample preparation, and technology limitations affecting implementation (1)

Flow Cytometry

With the growing number of parameters in flow cytometry panel design, new analysis methods such as spectral unmixing are crucial to handle high-dimensional data accurately and avoid false positives. Designing effective staining panels for modern flow cytometry requires expertise and optimization, considering factors like reagent compatibility and stability. Careful panel design is essential for successful flow cytometry experiments (2) (3).

Challenges

Challenges in manually mixing antibody panels can be daunting:

  • Tedious and time-consuming process: Manually pipetting, capping and de-capping tubes, and mixing multiple antibodies for each sample is labor-intensive (3).
  • Accuracy and consistency: Finding the correct antibody concentrations, particularly with large panels, can be tricky. (4)
  • Scalability and throughput: The manual process struggles with increasing numbers of antibodies or samples (5).
  • Risk of contamination and errors: Handling multiple antibodies manually raises the risk of cross-contamination (6).

In summary, manual antibody panel mixing presents challenges like time-consuming processes, concentration consistency, stability maintenance, scalability constraints, and a higher likelihood of errors and contamination.

Our Solution

Panel Mixing with the Parhelia Spatial Station™: Our P54 module securely holds 54 uncapped antibody vials with a silicone membrane for protection. When an antibody needs to be aspirated, the pipette tip will pierce the silicone membrane before drawing from the source. The entire P54 module can be further sealed with a lid and placed directly into a refrigerator at 4C for storage.

Recommended Product

Discover the Spatial Station™ from Parhelia Biosciences, a revolutionary new sample prep platform. It simplifies workflows, customizes panel mixing, and excels in multi-omics with unmatched control. A perfect companion to your multi-omic lab for automating complicated sample preparation protocols. Eliminate the need for individual, manual tube handling with an all‑in‑one solution antibody mixing and storage with the panel mixing modules in the Parhelia Spatial Station.

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Automated Panel Mixing with the Parhelia Spatial Station™ for Spatial Biology and Flow Cytometry. Copy 4

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